Postdoctoral Researcher in Mitochondrial Function
1 week ago
Postdoctoral Researcher in Mitochondrial Biology (Wredenberg Group)
Are you interested in advancing human health through research?
The Division of Molecular Metabolism focuses on elucidating the mechanisms that regulate mitochondrial activity and the implications of mitochondrial dysfunction in various diseases and the aging process. Our goal is to gain insights into disease mechanisms and to innovate therapeutic strategies. We are looking for 1-2 dedicated postdoctoral researchers to become part of Anna Wredenberg's research team.
About the Wredenberg Group
Our research encompasses both fundamental and translational studies of mitochondrial functions, investigating everything from mitochondrial gene regulation to the molecular impacts of metabolic disturbances in individuals with mitochondrial disorders. We employ a blend of genetic and biochemical methodologies on patient samples, genetically modified Drosophila melanogaster, and Mus musculus models. Additionally, we explore the interplay of mitochondria within the broader metabolic framework.
To learn more about our work, please visit the Division of Molecular Metabolism
Located in the state-of-the-art Biomedicum laboratory at the Solna campus of Karolinska Institutet, the Division of Molecular Metabolism, within the Department of Medical Biochemistry and Biophysics, conducts both biochemical and genetic investigations of patients with inherited metabolic disorders alongside basic scientific inquiries into mitochondrial metabolism regulation. We provide an exceptional research environment that fosters collaboration between basic and clinical sciences, particularly at the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital. Researchers have access to cutting-edge resources in molecular and cellular biology, as well as national core facilities at the Science for Life Laboratory.
Responsibilities
Mitochondrial dysfunction is a critical factor in numerous rare and common diseases and is significantly associated with age-related conditions and the natural aging process. As a postdoctoral researcher, you will delve into cellular mechanisms that counteract mitochondrial dysfunction and the buildup of mtDNA mutations. The Wredenberg group employs biochemistry, molecular biology, and contemporary omics techniques to investigate the molecular pathways underlying mitochondrial dysfunction and aging. Furthermore, in vivo modeling using fly and mouse models, including conditional knockout strains, will be integral to this research.
Candidate Profile
We welcome applications from enthusiastic individuals holding a PhD in molecular biology or genetics. While prior experience in mitochondrial research is not mandatory, familiarity with biochemistry, molecular biology, mouse genetics, and various omics methodologies is advantageous. Candidates with expertise in big data handling and bioinformatics are particularly encouraged to apply. Strong documentation skills and proficiency in both spoken and written English are essential. Successful candidates should demonstrate the ability to collaborate effectively within a team environment. Personal suitability will be a key factor in the evaluation process.
Entry Requirements
Postdoctoral Scholarship
Scholarships for postdoctoral qualifications can be offered to international researchers who seek to enhance their qualifications in Sweden. The objective of these scholarships is to promote international collaboration and support research qualifications following the completion of a doctorate or equivalent. A scholarship for postdoctoral research may be granted for a maximum of two years within a four-year timeframe after obtaining a doctoral degree or its equivalent. To qualify for a postdoctoral scholarship, candidates must possess a doctorate or a foreign degree considered equivalent. Applicants who have not yet completed their doctorate by the application deadline may still apply, provided they meet all requirements for degree completion before the intended start date of the postdoctoral training.
The department head will determine whether previous training and academic qualifications align with a Swedish doctorate or higher.
Type of Scholarship
The scholarship amount is tax-exempt and is set for twelve months at a time, disbursed biannually. In exceptional circumstances, shorter durations may be considered.
Postdoctoral Employment
To qualify for postdoctoral employment, candidates must possess a doctoral degree or a foreign degree deemed equivalent. This eligibility requirement must be fulfilled by the time of the employment decision. It is advantageous if the doctoral degree was completed within the last three years; however, earlier completion may be considered under special circumstances.
What We Offer
A stimulating and creative environment enriched with diverse expertise and interests. Karolinska Institutet is recognized as one of the leading medical universities globally. We conduct impactful medical research and offer a comprehensive range of medical education in Sweden. At KI, you will engage with researchers across various specializations and methodologies, providing ample opportunities for knowledge exchange and collaboration across scientific disciplines within medicine and health. The collaborative efforts have propelled KI to the forefront of global research. Many healthcare professionals have received their education at KI, and a strong partnership with healthcare providers is crucial for fostering high-quality education and research.
Application Process
Applications must include the following documents in English or Swedish:
- A complete curriculum vitae, detailing the date of thesis defense, thesis title, previous academic positions, academic titles, current position, academic distinctions, and committee work
- A comprehensive list of publications
- A summary of current work (maximum one page)
We look forward to receiving your application.
Make a meaningful impact in health research.
Type of employment: Postdoctoral studies. Contract type: Full-time. Salary: Scholarship or monthly salary. Number of positions: 1. Full-time equivalent: 100%.
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