Preclinical Bioinformatics Lead
2 days ago
Select how often (in days) to receive an alert:
Team: R&D, Pharmacovigilance & Regulatory Affairs
Job Type: Direct Employee
Contract Type: Permanent
Location:
Europe - remote, SE
About us
Based in Parma, Italy, Chiesi is an international research-focused pharmaceutical and healthcare group with over 85 years’ experience, operating in 31 countries with more than 7,000 employees. To achieve its mission of improving people’s quality of life by acting responsibly towards society and the environment, the Group researches, develops and markets innovative drugs in its main therapeutic areas.
We are proud to be the largest global pharmaceutical group to be awarded B Corp Certification, a recognition of high social and environmental standards. We are a reliable company that adopts and promotes a transparent and ethical behavior at all levels.
We believe that the success of Chiesi is built and shaped by our people and our strong set of shared Values and Behaviors. Our people make a critical difference to our success, which is why it is vital that we attract and retain the right talent who will continue to enrich our culture by living and breathing our values and behaviors.
In fact, we are a global family made up of different cultures, different genders, generations, ethnicities, abilities, sexual identities and many other enriching diversities.
Chiesi Research & Development
Our R&D team represents a fundamental asset for the business. It is divided into integrated functional areas focusing on pipeline projects including discovery and preclinical research, global technical development, drug delivery technology, clinical development, regulatory affairs, pharmacovigilance, intellectual property, quality assurance, R&D project and portfolio management.
Who we are looking for
Purpose
As a Bioinformatics Lead you will be a part of the PPM & R&D Digital Strategy and Execution Support Unit within R&D Project & Portfolio Management organization at the company.
Main Responsibilities
1. Provide bioinformatic expertise to address a wide variety of biological questions by analyzing and interpreting data, generating reports and building systematic internal data repositories.
2. Conduct omics analyses towards target identification and drug mode of action characterization with emphasis on transcriptomic (scRNA-seq), genomic (WGS, WES), and proteomic (MS, Olink) data, to be connected with patient strata and clinical data.
3. Design, build and monitor analysis pipelines of molecular data and omic data (e.g. Nextflow / Snakemake) using cloud computing solutions (AWS, Azure) and code repositories (e.g. Gitlab).
4. Perform initial quality control checks (pre-processing and cleaning) and downstream analysis on data coming from -omics studies.
5. Perform multi-omic data integration approaches, network analysis, and pathway-level statistical analysis to generate new hypotheses and collaborate with scientists on data mining and guiding experimental design.
6. Collect, QC and homogenize public data sets towards their analysis and integration with internally-generated data, provide input to systematic multi-omic data repository creation and management towards drug repositioning.
7. Coordinate and oversee data analysis with external service providers.
Experience Required
1. PhD in bioinformatics and/or computational biology, with a strong biological/medical background, and minimum of 5 years’ post-graduate experience.
2. Proficiency in analyzing NGS and single-cell analysis and subcellular analysis and other ‘omics’ data using statistical programming languages (e.g., R/Bioconductor, Python, etc.).
3. Demonstrated track record of applying bioinformatic analysis, including machine learning techniques and network biology, to integrate and analyze omic and clinical data, preferably within respiratory drug development.
4. Broad understanding of drug discovery and development, particularly early and late-stage development.
5. Strong publication record as a leading author.
Languages
What we offer
You would join a dynamic, fast-growing, challenging and friendly environment. In Chiesi we firmly believe that our people are our most valuable asset, that is why we invest in continuous training, learning and development. Therefore, we strive to continuously promote and satisfy development needs, paying particular attention to the quality of our working environment and to collective well-being.
We want our people to come to work happy every day, and we know how important it is to find the right work-life balance in order to be able to give our best. That is why we offer flexible working approach, remote working, support in the relocation process, tax assistance service for foreign colleagues and many other people-care services.
#J-18808-Ljbffr
-
Bioinformatics Team Lead
3 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeOur R&D TeamOur R&D team represents a fundamental asset for the business. It is divided into integrated functional areas focusing on pipeline projects including discovery and preclinical research, global technical development, drug delivery technology, clinical development, regulatory affairs, pharmacovigilance, intellectual property, quality assurance, R&D...
-
Preclinical Data Scientist Manager
24 hours ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeAbout the RoleWe are looking for an experienced Preclinical Data Scientist Manager to join our R&D team at Chiesi Farmaceutici S.p.A. The successful candidate will be responsible for managing a team of data scientists in analyzing and interpreting preclinical data, with a focus on -omics studies.The ideal candidate will have a strong background in...
-
Bioinformatics Lead
16 hours ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeAbout Us Chiesi Farmaceutici S.p.A. is a leading international research-focused pharmaceutical and healthcare group with over 85 years of experience. Operating in 31 countries with more than 7,000 employees, we aim to improve people's quality of life by acting responsibly towards society and the environment. We are proud to be the largest global...
-
Bioinformatics Team Lead
24 hours ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeJob DescriptionWe are seeking a skilled Bioinformatics Team Lead to join our R&D team at Chiesi Farmaceutici S.p.A. The successful candidate will lead a team of bioinformaticians in analyzing and interpreting complex biological data, with a focus on transcriptomic, genomic, and proteomic studies.The ideal candidate will have a strong background in...
-
Lead Bioinformatician
3 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeCompany OverviewChiesi Farmaceutici S.p.A. is a leading international research-focused pharmaceutical and healthcare group with over 85 years' experience, operating in 31 countries with more than 7,000 employees. We are dedicated to improving people's quality of life by acting responsibly towards society and the environment.We believe that our success is...
-
Bioinformatics Expert Lead
4 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeCompany OverviewChiesi Farmaceutici S.p.A. is a research-focused pharmaceutical and healthcare group with over 85 years' experience, operating in 31 countries with more than 7,000 employees. Our mission is to improve people's quality of life by acting responsibly towards society and the environment.We are proud to be the largest global pharmaceutical group...
-
Preclinical Data Analyst Manager
4 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeJob DescriptionAs a Bioinformatics Lead, you will be part of the PPM & R&D Digital Strategy and Execution Support Unit within R&D Project & Portfolio Management organization at Chiesi. Your main responsibilities will include:• Providing bioinformatic expertise to address a wide variety of biological questions by analyzing and interpreting data, generating...
-
Senior Data Analyst
3 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeChiesi Farmaceutici S.p.A. is an international research-focused pharmaceutical and healthcare group with a strong commitment to innovation and excellence. As a Bioinformatics Lead, you will join a dynamic and fast-growing team that is dedicated to improving people's quality of life by acting responsibly towards society and the environment. You will be part...
-
Computational Biology Specialist
16 hours ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeCompany Overview At Chiesi, we are committed to improving people's quality of life by acting responsibly towards society and the environment. As a leading international research-focused pharmaceutical and healthcare group, we operate in 31 countries with over 7,000 employees. We are proud to be the largest global pharmaceutical group to be awarded B Corp...
-
Lead Bioinformatician
24 hours ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeKey ResponsibilitiesWe are seeking an experienced Lead Bioinformatician to join our R&D team at Chiesi Farmaceutici S.p.A. The successful candidate will lead a team of bioinformaticians in analyzing and interpreting complex biological data, with a focus on transcriptomic, genomic, and proteomic studies.The ideal candidate will have a strong background in...
-
Computational Biology Specialist
4 days ago
Stockholm, Stockholm, Sweden Chiesi Farmaceutici S.p.A. Full timeRequired Skills and QualificationsTo be successful in this role, you will need to have a strong background in bioinformatics and computational biology, with a PhD degree and minimum 5 years post-graduate experience. Your skills should include proficiency in analyzing NGS and single-cell analysis and subcellular analysis and other 'omics' data using...
-
Stockholm, Stockholm, Sweden TN Sweden Full timeKarolinska Institutet is one of the world's leading medical universities, and we are proud to be part of it. Our research group is dedicated to advancing our understanding of epithelial tissue development and contributing to better health outcomes.Why Join UsYou will have the opportunity to work on a challenging project that requires expertise in stem cell...
-
Scientific Researcher Opportunity
3 days ago
Stockholm, Stockholm, Sweden QRIOS Full timeJob DescriptionQRIOS Life Science is seeking a highly skilled consultant to join the Preclinical team at Chiesi, a leading global research-focused pharmaceutical company. As a key member of our team, you will be responsible for contributing to the development of discovery projects in the field of rare diseases.Your primary responsibilities will include...
-
Characterizing Progenitor Cell Dynamics
6 days ago
Stockholm, Stockholm, Sweden TN Sweden Full timeWe are a leading research group at Karolinska Institutet dedicated to understanding the complex processes of epithelial tissue development. Our research focuses on the establishment of esophageal progenitor cell niches during development.Our GoalsAs a postdoctoral researcher, you will contribute to our goals by analyzing and interpreting large-scale...
-
Stockholm, Stockholm, Sweden Karlstad University Full timeWe are looking for a highly skilled postdoctoral researcher to join our team at Karolinska Institutet, where we conduct pioneering research in developmental biology and organ architecture.Our TeamOur laboratory is part of the Department of Cell and Molecular Biology at Karolinska Institutet, located in the BioMedicum Solna campus. We are a collaborative,...
-
Senior Developmental Biology Researcher
2 days ago
Stockholm, Stockholm, Sweden Karlstad University Full timeJoin a world-class research team at Karolinska InstitutetWe are seeking a highly motivated postdoctoral researcher to join our innovative project on embryonic cell fate lineages with unprecedented resolution. The successful candidate will be part of a dynamic and collaborative environment, working alongside expert scientists in developmental biology and...
-
Stockholm, Stockholm, Sweden Karlstad University Full timeAt Karolinska Institutet, we are seeking a highly motivated postdoctoral researcher to join our innovative ERC-funded project focused on resolving embryonic cell fate lineages with unprecedented resolution.Company OverviewKarolinska Institutet is one of the world's leading medical universities, conducting successful medical research and offering a wide range...
-
Stockholm, Sweden Karlstad University Full timePostdoctoral Researcher in Developmental Biology with in utero next generation single cell lineage tracingDo you want to contribute to top quality medical research?Description of the Andersson labThe Andersson Lab is dedicated to uncovering the mechanisms that guide organ systems to develop their correct cellular identities and architectures. As...
-
Associate Professor
3 weeks ago
Stockholm, Sweden University of New South Wales Full timeApply now Job no: 527792 Work type: Full Time Location: Sydney, NSW Categories: Associate Professor - Salary (Level D) - AUD $179,630 to $197,312 per annum + 17% superannuation - Full time - Location: Kensington – Sydney, Australia The Opportunity Join the School of Computer Science and Engineering (CSE) in the Faculty of Engineering as an Associate...
