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Doctoral Student Position in Translational Medicine in Rheumatology with a Focus on B Cell Biology and Antibody Engineering
2 months ago
We are seeking a highly motivated and talented doctoral student to join our research group at the Department of Medicine, Solna. The successful candidate will have the opportunity to work on a cutting-edge research project in translational medicine in rheumatology with a focus on B cell biology and antibody engineering.
Research GroupThe Division of Rheumatology is an active and internationally successful research unit that conducts clinical, experimental, and epidemiological research in close collaboration with the rheumatology clinic at the Karolinska University Hospital, Solna. Our research group has a leading role in several national and international consortia and networks.
Project DescriptionThe project is focused on studies of autoantibodies and B cells in systemic lupus erythematosus (SLE). SLE is an autoimmune disease with multiorgan involvement and dysregulation of the adaptive immune system, in particular B cells. The successful candidate will study the role of B cells and autoantibodies in the SLE pathogenesis by B cell phenotyping, serological screening, BCR repertoire, and single-cell analysis, and by generation of monoclonal antibodies from patient B cells.
ResponsibilitiesThe doctoral student will be responsible for performing practical laboratory work, contributing to experimental design, optimization of methods, analysis of data, and presentation of results. The student will also participate in courses, seminars, and conferences.
RequirementsTo be eligible for this position, the candidate must have a background in biotechnology, medicine, or biomedicine and a strong interest in immunology. Practical experience of techniques such as PCR, protein engineering, antibody assays, transcript analysis, cell culture, and/or flow cytometry is expected. Knowledge in data analysis and bioinformatics is also beneficial. The candidate must be willing to work with human blood and tissue samples.
What We OfferWe offer a creative and inspiring environment full of expertise and curiosity. As a doctoral student, you will have the opportunity to work on a research project under the supervision of experienced researchers and follow an individual study plan. You will also have access to our modern gym and receive reimbursements for medical care.
Eligibility RequirementsTo participate in the selection for a doctoral position, you must meet the following general and specific eligibility requirements:
- Have been awarded a second-cycle/advanced/master qualification (i.e., master degree), or
- Have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
- Have acquired substantially equivalent knowledge in some other way in Sweden or abroad.
You must also show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.
How to ApplyTo apply for this position, please submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.
