Postdoctoral Researcher in Integrative Structural Biology of Fertilization

2 days ago


Huddinge Municipality, Sweden Karolinska Institutet Full time

At Karolinska Institutet, we are seeking highly motivated postdoctoral researchers to join our team in the Department of Biosciences and Nutrition. We offer a unique opportunity to contribute to top-quality medical research in the field of integrative structural biology of fertilization.

Key Responsibilities:

  • To identify and characterize key protein-protein interactions mediating gamete recognition and fusion across the evolutionary tree
  • To combine cryo-EM and X-ray crystallography with artificial intelligence-based protein structure predictions to shed light on the molecular mechanism of egg-sperm interaction at fertilization

About the Role:

We are looking for two Postdoctoral fellows to join Professor Luca Jovine's research group. The successful candidates will have significant hands-on experience in mammalian and/or insect cell expression, purification, and biochemical characterization of proteins. Experience in analyzing protein-protein interactions using different techniques and approaches is also required.

Requirements:

  • A doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree
  • Experience in using experimental and/or computational structural biology to study protein-protein interactions, particularly in the context of biological systems that involve membrane proteins
  • Fluency in English (both written and oral)

What We Offer:

This position is a temporary contract as a Postdoc for two years. There is a possibility for extension depending on funding availability. We offer a competitive salary, approximately 63,000 SEK per month, plus additional benefits such as access to state-of-the-art equipment, training opportunities, and a collaborative work environment.

Location: Campus Flemingsberg

About Karolinska Institutet: We are one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Our vision is to make a significant contribution to the improvement of human health; our mission is to conduct research and education that shape the future.



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