Photoreceptor Generation Researcher

22 hours ago


Solna Municipality, Sweden Karlstad University Full time
About the Role

We are seeking a highly skilled Postdoctoral Researcher to join our team at Karolinska Institutet. The successful candidate will work in our lab to develop an efficient method for generating photoreceptors from pluripotent stem cells.

As a Postdoctoral Researcher, you will be responsible for culturing and differentiating pluripotent stem cells, isolating cells, conducting genetic analysis, and using microscopy to test the functionality of the generated photoreceptors.

This project aims to develop a clinically compatible method for producing photoreceptors that can be used for the treatment of Retinitis Pigmentosa and age-related macular degeneration.

About the Project

The project focuses on developing a method for differentiation of pluripotent stem cells into photoreceptors. This involves several steps, including culturing and differentiating pluripotent stem cells, cell isolation, genetic analysis, and microscopy.

The generated photoreceptors will then be tested in animal models together with Professor Anders Kvanta and Dr. Filippo Locri. Once functionality has been demonstrated in animal models, the work will focus on making the method clinically compatible for future clinical trials.

About You

To be eligible for employment as a postdoctor, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. Completion of your doctoral degree within the last three years is considered an advantage.

  • Experience in differentiation of pluripotent stem cells is highly advantageous.

It is also beneficial if you have experience in retinal developmental biology or production of retinal cell types, flow cytometry, cell sorting, microscopy, clinical cell production, and GMP.

As a person, you are expected to have strong collaboration and communication skills, be analytical, solution-oriented, and work independently with a drive to deliver results.



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