Doctoral (PhD) student position in cancer immunotherapy

2 days ago


Stockholm, Sweden Varbi Recruit Full time

Doctoral (PhD) student position in cancer immunotherapy

Do you want to contribute to improving human health?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Associate Professor Dr Mattias Carlsten M.D. Ph.D. is heading a translational research group at Karolinska Institutet (KI) with close connection to the medical unit Cell Therapy and Allogeneic Stem Cell Transplantation (CAST) at the Karolinska University Hospital. The group focuses on studying how NK cells can be utilized to treat cancer. More specifically, the group focuses on understanding basic biology and how to genetically engineer NK cells to improve their in vivo persistence and homing to the tumor for enhanced anti-tumor efficacy.

The doctoral student project and the duties of the doctoral student

This project will focus on the development of CRISPR-based approaches to genetically introduce or remove molecules/elements that can augment the anti-tumor potential of NK cells. The overall goal is to establish proof-of-concept for in vivo editing of NK cells for augmented anti-tumor efficacy. The student will address the role of introducing CARs and supporting cytokines via homology-directed end joining (HDR) for redirected tumor cell targeting. The project will involve various cellular and molecular biology techniques and assays such as flow cytometry, electroporation, and ELISA.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world's leading medical universities. As a doctoral student, you will be offered an individual research project, a well-educated supervisor, and opportunities for international exchanges.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements:

A) General eligibility requirement:

- Have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
- Have satisfied the requirements for courses comprising at least 240 credits, with at least 60 credits awarded in the advanced/second-cycle/master level.

B) Specific eligibility requirement: Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

We are seeking a highly talented individual who holds a Medical Doctor degree with experience in cell and/or gene therapy. The student should have a background in immunology and cell signaling, with critical merits in running immunology assays and conducting cell culture work.

Terms and conditions

The doctoral student will be employed on a doctoral studentship for a maximum of 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Your application must contain the following documents:

- A personal letter and a curriculum vitae
- Degree projects and previous publications, if any
- Documents certifying your general and specific eligibility

Selection

A selection will be made among eligible applicants based on the ability to benefit from doctoral education.

Want to make a difference? Join us and contribute to better health for all

Type of employment: PhD placement

Contract type: Full time

Number of positions: 1

City: Stockholm

Country: Sweden

#J-18808-Ljbffr



  • Stockholm, Sweden Karlstad University Full time

    Doctoral (PhD) student position in Precision Psychiatry Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is...


  • Stockholm, Sweden Karlstad University Full time

    Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required. The Department of Medical Epidemiology and...


  • Stockholm, Stockholm, Sweden Varbi Recruit Full time

    **Project Overview**This project aims to develop novel CRISPR-based approaches for enhancing the anti-tumor potential of NK cells. The successful candidate will work closely with the research team to design and execute experiments, and will have the opportunity to collaborate with international partners.Key Objectives:Develop CRISPR-based approaches for...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH Third-cycle subject: Technology and health Machine Learning-Accelerated Virtual Testing for Automotive Head Impacts This PhD project is part of a collaboration between Autoliv Development AB and Royal Institute of Technology - KTH. Virtual testing based on finite element (FE)...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral student in protein design for improved terpene biosynthesis School of Engineering Sciences in Chemistry, Biotechnology and Health at KTH Syrén's research group is recruiting a PhD student in protein design applied to terpene biosynthesis. The project, funded by EU (HORIZON-TMA-MSCA-DN), involves international research groups and exchanges with...


  • Stockholm, Sweden Karlstad University Full time

    Since its founding in 1827, KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities. Project Description Third-cycle subject: Technology and health Machine Learning-Accelerated Virtual Testing for Automotive Head Impacts. This PhD project is part of a collaboration between Autoliv...


  • Stockholm, Sweden Varbi Recruit Full time

    1-2 doctoral students in computational pathology and medical artificial intelligence Do you want to contribute to top quality medical research? To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of...


  • Stockholm, Stockholm, Sweden Varbi Recruit Full time

    **About the Role**We are seeking a highly skilled and motivated PhD researcher to join our translational research group at Karolinska Institutet. The successful candidate will be working on a project focused on developing CRISPR-based approaches to genetically introduce or remove molecules/elements that can augment the anti-tumor potential of NK cells.Key...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    School of Electrical Engineering and Computer Science at KTH Third-cycle subject: Computer Science CLEAR-BOT (CoLlaborative intElligence for human-Aligned RoBOTs) is a project that aims to align robot learning with human intentions. Current AI systems often miss the nuances of human intentions, leading to unintended consequences. We aim to develop robots...


  • Stockholm, Stockholm, Sweden KTH Royal Institute of Technology Full time

    Job DescriptionThis PhD position involves conducting experiments and numerical modelling on bitumen emulsions, binders, and CMA mixtures. You will also use Finite Element analyses and a Life Cycle Assessment framework to evaluate the impact of the CMA technology on road sustainability.The successful applicant will be employed by KTH for the first two years...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral students in Large Language Model inferencing School of Electrical Engineering and Computer Science at KTH Third-cycle subject: Computer Science The advertised doctoral student positions are within an ambitious, 5-year Wallenberg Scholar project titled “Scalable and adaptive inferencing for democratizing AI.” In this 18 Million SEK project, we...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    School of Architecture and Built Environment at KTH Third-cycle subject: Civil and Architectural Engineering This project is funded by the Swedish Competence Centre in Road Technology (KCV) for four years. The aim of the project is to increase the knowledge about Cold Mix Asphalt (CMA) – a technology that reduces resource usage, energy consumption, and...


  • Stockholm, Sweden Karlstad University Full time

    Doctoral student in learning and optimization for edge computing The Division of Network and Systems Engineering is looking for one doctoral student with a very strong background and interest in system modeling, optimization, and machine learning. The successful candidate will join a MSCA Doctoral Network project on developing rigorous, novel tools for safe...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral student in hybrid control of multi-agent systems School of Electrical Engineering and Computer Science at KTH Third-cycle subject: Electrical Engineering The project involves distributed task planning and control for multi-agent systems. Multi-agent tasks will be given in the form of formal verification languages such as temporal logic and its...


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral student in occupational exposure assessment for the green transition KTH Royal Institute of Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health Third-cycle subject: Technology and Health There is an intensifying transition towards ‘plug-in’ cars, and as the existing fleet gets older, the repair needs increase....


  • Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral student in Applied Mathematics (spec. Mathematical Statistics) School of Engineering Sciences at KTH Third-cycle subject: Doctoral program in Applied and Computational Mathematics This doctoral project focuses on problems at the intersection of probability theory, stochastic analysis and optimization that have bearing on financially motivated...

  • Doctoral student

    6 days ago


    Stockholm, Sweden KTH Royal Institute of Technology Full time

    Doctoral student (licentiate) in building energy system control School of Architecture and Built Environment at KTH Third-cycle subject: Architectural and Civil Engineering In the transition toward low-energy buildings and the 5th generation of district heating, using data-driven approaches to integrate decentralized renewables with optimal control will...


  • Stockholm, Stockholm, Sweden KTH Royal Institute of Technology Full time

    The KTH Royal Institute of Technology invites applications for a PhD researcher position in distributed multi-agent planning. The project involves the development of novel algorithms for distributed multi-agent planning and control under complex tasks, taking into account information from other agents and changes in the environment. The doctoral student will...


  • Stockholm, Stockholm, Sweden Naturhistoriska Riksmuseet Full time

    The Swedish Museum of Natural History is seeking a highly motivated and talented researcher to join our team in the Department of Bioinformatics and Genetics. As a PhD student in this position, you will contribute to the analysis of population-level genomic data from museum bird samples and develop new bioinformatic tools for understanding the evolution of...


  • Stockholm, Stockholm, Sweden Varbi Recruit Full time

    **Doctoral Studies**As a doctoral student at Karolinska Institutet, you will be part of a dynamic and innovative research environment. You will work closely with experienced researchers and will have the opportunity to design and execute your own research project.Key Responsibilities:Design and execute experiments to investigate the anti-tumor potential of...