Senior Scientist Bioscience Cardiovascular

Job description

Senior Scientist, In Vitro Cardiovascular Biology

Do you have expertise within in vitro cardiovascular biology and enjoy working in the lab? Would you like to apply your expertise in a global company that is accelerating innovative science and turn ideas into life changing medicines? Join us to discover future treatment of Cardiovascular, Renal and Metabolic diseases

At AstraZeneca, we work at the cutting edge of science to develop the ground-breaking medicines of the future – here we do things that have never been done before. We put patients first and strive to meet their unmet needs worldwide.

CVRM is one of three main therapeutic research areas within AstraZeneca. Early CVRM has a patient-centric approach for discovering novel treatments for patients with cardiovascular-, chronic kidney- and metabolic disease and delivers candidate drugs into late-stage clinical development. In the Bioscience Cardiovascular department, we focus on identifying and validating new drug targets for treatment of patients with cardiovascular disease and heart failure, as well as evaluating pharmacological aspects, e.g. efficacy and mechanism of action, of potential new drug candidates. The in vitro team delivers key data to projects across all phases of the drug discovery and development process, and we work with different modalities such as small molecules, modified mRNA, antibodies, cell therapy, antisense oligonucleotides and peptides.

We are now recruiting a Senior Scientist with expertise in cardiovascular biology to join the Bioscience Cardiovascular in vitro team within the Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca in Gothenburg, Sweden.

This is a consultant assignment with Randstad Life Sciences. Randstad Life Sciences is specialized in competences within Life Science. As a consultant you get a competitive salary, benefits and collective agreements. Your consultant manager ensures that you get varying and developing assignments at different companies, within different industries. At Randstad Life Sciences, your personal development is in focus, and you are offered a large network and many social activities.

Deadline 2024-02-27 - the selection process and interviews will be ongoing, so please apply as soon as possible

Responsibilities

As a Senior Scientist you will play a key role in driving science and projects within the cardiovascular area forward. This is a lab-based role where you will explore novel drug targets with key in vitro data. Collaboration is critical for successful delivery of drug projects, and you will work closely with scientists/teams from a wide range of different functions within AstraZeneca as well as with external partners and collaborators. You will work with in vitro biology using cell lines, pluripotent stem cells (PSC) and primary cardiovascular cells along with molecular and functional biology techniques. You will have the opportunity to try novel techniques and ideas required for progressing existing portfolio and novel science. Responsibilities include:

- Independently design, develop and run in vitro studies and assays for target identification and validation
- Work with molecular biology methods, imaging and assays for functional readouts such as contractility and cardiac metabolism
- Contribute to communications of scientific findings through publications in scientific journals and at meetings
- Proactively contribute to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared

Qualifications

Essential for the role:

- PhD or master’s degree in biology, pharmacology, cardiovascular disease or similar
- Strong experience in cell and molecular biology, biochemistry and relevant in vitro/ex vivo assays within the cardiovascular area
- Experience in handling and manipulating relevant PSC cells and primary human and animal cardiac cell types, including cardiomyocytes
- Excellent English communication skills, both spoken and in writing

Desirable for the role:

- Experience with cardiomyocyte biology and function in healthy and diseased systems
- Background in drug discovery and development in the pharmaceutical industry
- Background in Vivo and in Vitro

About the company

Randstad

At Randstad, we see the possible in people. With business all over Sweden and in all areas of expertise, we help people find work that feels good, where they get the opportunity to develop and realize their true potential.

With close to 600 000 employees in 38 countries, Randstad is the global leader in the HR services industry. Our mission is to become the world’s most valued working life partner. By combining our passion for people with the power of today’s technology, we support people and organizations in realizing their true potential. We call it Human Forward.