Process Development Scientist/Sr. Scientist

2 weeks ago

Stockholm, Stockholm, Sweden The SmartCella Group Full time

At Procella Therapeutics we provide advanced capabilities within stem cell therapy development and have inhouse cGMP manufacturing. We have a globally licensed cardiac stem cell therapy in clinical stages (collaboration with AstraZeneca) and a growing pipeline of stem cell therapies.

We are now seeking moreScientists/ Sr. Scientiststo join our Process Development team.

Position overview

As a Senior Scientist /Scientist you will work in the process development group, proposing the scientific direction of ongoing work and supporting/executing associated wet lab activities to deliver on project objectives. In this role, you will be working closely with other colleagues in an agile, multidisciplinary environment, to deliver innovative cell therapies and/or novel technology solutions to accelerate the translation of cell therapies to clinic. The Senior Scientist / Scientist may be tasked with performing process development, QC testing, product manufacturing, or analytical method development depending on the prevailing project goals of the company.

Key responsibilities

Your contributions and responsibilities will be:

  • Drive the scientific direction of various projects by proposing development strategies, designing experiments, coordinating teams and planning of ongoing labwork.
  • Delivery of project objectives on time, on budget, and to a suitable level of quality to meet project milestones, including participating in daily labwork.
  • Preparation of data reports and present data to internal or external stakeholders.
  • Routine laboratory and equipment maintenance operations, including cleaning of lab areas and equipment, correct use and maintenance of lab equipment, ensuring availability of raw materials and consumables and support for overall inventory and budget management.
  • Drafting of SOPs and performing training of staff.

Required qualifications and competence

To be successful in the position you need:

  • PhD in a relevant subject area, or BSc and/or MSc in a relevant subject area with 3+ years' relevant work experience for the Scientist position.
  • PhD in a relevant subject area, and 4+ years' relevant work experience, or BSc and/or MSC in a relevant area and 6+ year's relevant work experience for the Senior Scientist position.
  • Demonstrable experience with bioprocess development either in Biopharma, CDMO or a similar organization, including demonstrable expertise in Design of Experiments, bioreactors, upstream/downstream bioprocessing of cells.

And/or

  • A strong background in developmental biology, working withpluripotent stem cells, use, development, and optimization ofdifferentiation methods to cardiac, neuronal or other therapeutically relevant cell types.
  • Knowledge and prior practical experience with relevant analytical methods such as flow cytometry, qPCR, or ddPCR.
  • Proficient in use of MS Office tools.
  • Fluent in written and spoken English and have excellent interpersonal and communication skills, both written and verbal.

It will be a merit if you have prior experience/knowledge/can demonstrate:

  • Cell and gene therapy product development in an industry setting.
  • Previous experience working with bioprocessing equipment (for example:bulk electroporation, cell sorting (magnetic or fluorescence based), buffer exchange, vialling, controlled rate freezing).
  • Innovative and entrepreneurial mindset.
  • Working under a quality system.
  • Project and people management.
  • Familiarity with Lean, Six Sigma, or similar methodologies.
  • Quality by Design methodology.
  • Working under GMP.

Interested? Submit your application today We will review applications on an ongoing basis and hope to fill the position as soon as possible.

SmartCella is a world-leading biotech & medtech company pioneering the future of targeted therapies by combining first-in-class delivery platforms with cutting-edge cell and gene therapies. The SmartCella group consist of SmartCella Holding AB, ProCella Therapeutics AB, SmartWise AB and SmartCella Solutions AB with a total of 60 employees from more than 20 nationalities.


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