PhD student positions in Biochemistry and Microbiology
5 days ago
Everybody knows what tree bark is, but very little is known regarding its degradation in nature. In this project, you will be able to break new ground on microbial bark degradation, from mapping which species are driving this process to identifying and characterizing the enzymes they produce. We are looking for two PhD students that together can work on this topic in a larger team together with postdocs and international collaborators.
Project description Tree bark is a renewable resource that is produced in huge amounts every year, but it is poorly used today. It contains regular wood polymers, such as cellulose and lignin, but also a large fraction of so-called extractive compounds that make it unsuitable for regular pulping processes. The extractives also have interesting roles as major defensive molecules protecting the tree from external threats, but still there is very little information on how bark and its extractives are broken down in nature.
In this project, which is part of a larger project funded by the Novo Nordisk Foundation, we will broadly investigate microbial bark degradation and aim to develop knowledge as well as new biotechnological methods to better valorize it. We will target both Nordic tree bark types and more tropical species.
The project will involve microbiology, various (meta-)omics analyses, molecular biology to clone and heterologously express genes of interest in either bacteria or yeast, protein production and purification, and detailed biochemical characterization of identified enzymes, including determination of substrate specificities and kinetics. Additionally, various chemical analyses will be important to understand what happens to the material or individual molecules during microbial or enzymatic treatments.
We expect to recruit 2 PhD students and to the larger project.
A collaborative mindset will be instrumental and expected from all team members, though each person will be able to pursue or drive more individual projects.
Information about the division and the department
The project will mainly be carried out at the with Associate Professor Johan Larsbrink as the main supervisor, and with Assoc. Prof. Merima Hasani from , Chalmers, as co-supervisor. IndBio is an interdisciplinary and highly international group of researchers which consists of around 45 members and > 20 nationalities. The research in the division revolves around microbiology and fermentation, enzymology, and molecular biology, with a general focus of using renewable raw materials for the sustainable production of fuels, chemicals and materials. In addition to independent research, being a part of IndBio also includes taking part in weekly division meetings, research group meetings, and various social activities such as a yearly division retreat. A large variety of scientific instruments are available in our shared laboratory facilities, and in addition several core facilities are available at the university and its close vicinity. includes three additional research divisions which provide additional expertise and equipment.
Major responsibilities
As a PhD student, you will be responsible for the daily management of your research project, including planning, performing experiments and critically analyzing your results. The laboratory work includes microbial cultivations, cloning, protein production and purification, enzymology, and chemical/material analyses. You will be expected to communicate your results in different settings, from meetings with supervisors and collaborators, to presentations at the research division and at international conferences. Additionally, you will be expected to develop your scientific writing skills by authoring articles for publication in scientific journals.
You will also be expected to teach on Chalmers' undergraduate level courses or performing other departmental duties, up to 20% of working hours, and attend courses both in subjects directly related to your research and in general "soft" skills such as project management, teaching, and writing. At the Division level, you will take part in the general maintenance of instruments and will have the opportunity to supervise MSc and BSc students.
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Gothenburg, Sweden Chalmers tekniska högskola Full timeHow bark is broken down by microbes is virtually a black box today, despite its importance to the tree and the huge amounts produced in industry. In this project, you will be part in a larger team to help break new ground on microbial bark degradation, from mapping which species are driving this process to identifying and characterizing the enzymes they...
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