Master Thesis – Advancing Bispecific Antibody Purification

3 days ago

Uppsala, Uppsala, Sweden myGwork - LGBTQ+ Business Community Full time 40,000 - 80,000 per year

This job is with Danaher, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.
Bring more to life.
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?

At Cytiva, one of Danaher's 15+ operating companies, our work saves lives—and we're all united by a shared commitment to innovate for tangible impact.

You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.

Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.

At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. Take your next step to an altogether life-changing career.

Learn about the Danaher Business System which makes everything possible.

At Cytiva, we are continuously innovating chromatography solutions to meet the evolving needs of biopharmaceutical manufacturing. Bispecific antibodies (bsAbs) represent a promising class of next-generation therapeutics, but their complex structure introduces unique challenges in downstream processing. In particular, the capture step must efficiently remove product-related impurities such as half-antibodies and homodimers.

Recent advancements in tailor-made affinity resins have shown improved purification outcomes compared to traditional resins. This thesis project will explore the performance of modern affinity resins in bsAb capture and assess their impact on overall process efficiency and sustainability.

What You'll Do
You will conduct lab-based experiments to:

  • Evaluate the separation performance of modern vs. traditional affinity resins in bsAb capture.
  • Analyze samples using techniques such as HPLC-SEC/RPC, MALS, electrophoresis, and fluorometric assays.
  • Assess process economics and environmental impact of different downstream purification workflows.

Depending on your interests and available resources, the project may also include:

  • Optimization of purification strategies for bsAbs.
  • Development of analytical methods to evaluate purification performance.

Who You Are

  • Master's student in Science or Engineering with a focus on chemistry, biochemistry, or biotechnology.
  • Eligible for master thesis work between January 2026 – June 2026.
  • Background in chromatography is advantageous.
  • Independent, structured, and curious about biotherapeutic development.

Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.

For more information, visit

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