Master Thesis – Antibody purification and analysis
2 weeks ago
Bring more to life.
Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology?
At Cytiva, one of Danaher's 15+ operating companies, our work saves lives—and we're all united by a shared commitment to innovate for tangible impact.
You'll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher's system of continuous improvement, you help turn ideas into impact – innovating at the speed of life.
Working at Cytiva means being at the forefront of providing new solutions to transform human health. Our incredible customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, new medicines, and cell and gene therapies.
At Cytiva you will be able to continuously improve yourself and us – working on challenges that truly matter with people that care for each other, our customers, and their patients. Take your next step to an altogether life-changing career.
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At Cytiva, we are developing chromatography resins for processing biopharmaceuticals, such as antibodies. The purification of antibodies is divided into a capture and one to two polishing steps. The capture step is affinity chromatography that aims to isolate the target antibody from the cell culture suspension. In the following polishing step(s), the aim is to remove process and product-related impurities such as aggregated, fragmented or chemically modified Ab species as well as residual host-cell proteins (HCPs) and DNA. The polishing resin can vary; however, ion-exchange chromatography is commonly used. A variety of analytical techniques at each purification step are employed to ensure product purity and verify effective removal of impurities.
What You'll Do
Lab work aiming to evaluate separation performance of chromatography resins on Ab-related test material. This includes sample analysis using different detection methods, for example HPLC-SEC/RPC, MALS, electrophoresis or fluorometric assay. Depending on resources and the applicants' interests, the project focus can be either on optimization of a polishing process using start material with different impurity profiles or development of analytical method(s) for evaluation of purification performance.
Who You Are
- Master's student in Science or Engineering with a focus on chemistry, biochemistry, or biotechnology.
- Eligible for master thesis work between January 2026 – June 2026.
- Background in chromatography is advantageous.
- You like to work independently and with a structured approach.
Join our winning team today. Together, we'll accelerate the real-life impact of tomorrow's science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life.
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