Senior Associate Scientist, Plasmid

3 weeks ago

Sundsvall, Sweden Recipharm AB Full time
Senior Associate Scientist, Plasmid & Viral Vector Purification

ABOUT THE ROLE

ReciBioPharm is looking for an Associate/Senior Associate Scientist, Plasmid and Viral Vector Purification, who brings enthusiasm, intellectual curiosity, scientific rigor and a desire to drive fast growth. This role will work closely with both plasmid and viral vector process development team to develop innovative purification platform for plasmid and viral vector, as well as deliver customer projects to support exciting cell & gene therapy application. The successful candidate will have the vast growth opportunities via cross training through both plasmid and viral vector process development, tech transfer and scale-up for GMP manufacturing, and related analytics for process monitor and final product release.

MAIN TASKS & RESPONSIBILITIES

  • Apply knowledge and skills in chromatography and filtration technologies to lead the scalable process development for plasmid & viral vector purification.
  • Support and conduct analytical assays to characterize physical and biological properties of plasmid and viral vector via agarose gel electrophoresis, fragment analyzer, dot-blot, ELISA, ddPCR, FACS and/or other methods.
  • Work closely with cross-functional teams including upstream process development, analytics, engineering, GMP manufacturing and quality to ensure the delivery of customer projects.
  • Responsible for laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies.
  • Author, review and manage documents including laboratory notebooks, process development reports, technical transfer records, and process related documents.
  • Embrace ReciBioPharm value and culture, result oriented, work with can-do attitude, team player mentality, constantly inject positive energy into the working environment.

SKILLS AND EXPERIENCE

  • Degree in Molecular Biology or Biochemistry, or a related scientific field. B.S. with 3+ years of relative experience in a biotech/pharma setting.
  • Hands-on skills on AKTA with UNICORN control software and TFF filtration technologies for large molecules is a must.
  • Hands-on experience in plasmid and viral vector preparation and characterization is highly desired.
  • Hands-on experience in standard analytical technologies for plasmids including HPLC, agarose gel electrophoresis, capillary electrophoresis, qPCR, ELISA is a plus.
  • An ability to work independently, meet deadlines and prioritize work effectively. Must be able to thrive and deliver results on goals in a fast-paced, dynamic and highly multi-tasking environment.

WHAT WE OFFER/EMPLOYEE BENEFITS

  • Medical Benefits: Medical, Dental, Vision, Life, AD&D Insurance, Disability, FSA, HSA, Additional Voluntary Plans.
  • 401K Match.
  • Time off: PTO, sick time, floating holidays, and 9 company holidays.

LOCATION

Watertown, MA

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